The majority of drugs have an impact on the "reward circuit" in the brain, which results in pleasure and a flood of the chemical messenger dopamine in the brain. In order to thrive, a person has to engage in activities such as eating and spending time with loved ones on a regular basis. Dopamine rushes in the reward circuit are responsible for reinforcing dangerous behaviours like drug usage because of the reinforcement they provide. As a result, individuals are more likely to engage in the activity again.
If you keep using medications, your brain will adapt by lowering the ability of cells in the reward circuit to respond to it. While the person is still abusing drugs, this will continue to happen. When a person's tolerance for a substance wears off, the high they get from it isn't as intense as when they first started using it. They may be able to get the same effect by taking a larger amount of the chemical. As a result of these changes in brain function, the individual may discover that they are no longer able to enjoy activities such as eating or sexual engagement.
A number of cognitive and behavioural functions, such as learning, judgement, decision-making, stress, memory, and behaviour, might be affected by long-term use of these substances. Many people who take drugs, although being aware of the possible bad repercussions, continue to do so because of the nature of addiction.
Is there a reason why some people acquire a tolerance to drugs while others do not? Developing a drug addiction is a process that cannot be predicted by a single attribute. Several variables influence a person's probability of becoming addicted. Having more predispositional features increases the likelihood that a person may get addicted to drugs after using them.